Biotron LiFlus GS

LIFLUS GS

Easy View - Panel control system shows the measured values
Integrated Microprocessor controller
Powerful PC Monitoring software - graphic user interface
DO stat for using of the feed peristaltic pump or DO mode
(Motor speed controlled)

lifusgs

FEATURES 

*The LiFlus GS fermentation system is a lab scale fermentor which is designed for multi-pur-pose fermentation. The controller system is very easy to handle and all the monitored data and con-trol parameters are trans-mitted to the personal computer with using the RS-232C serial communi-cation protocol. The gra-phic user interface pro-gram shows the whole-status of the fermentation system in a real time con-dition.

* 4-peristaltic pumps are installed in the controller body that acid, base, anti-foam agent and media can be supplied to the fermen-tor. The various parame-ters for fermentation such as pH, DO, temperature and the rotating speed for the fermentor can be mo-nitored and controlled by the controller. Especially LiFlus GS has a special function of DO mode that the agitation speed can be governed by the DO sen-sor to control the DO va-lue for target range. The various accessories can be attached to the fermen-tation system. The various size of single vessel with hot plate or double vessel with water bath can be selected. The agitation motor is installed on the top plate and the top driv-ing mechanism can make the simple configuration and high reliability.

  • Various size of the single and double wall type vessel can be selected.
  • The top driving configuration with DC servo motor makes simple configuration of the head plate.
  • The rotating speed of the agitator can be modified and controlled from 50 to 1,200 rpm.
  • The pt-100 temperature sensor measures the precise temperature value.
  • The pH value precisely with the temperature and the value of dead-band for the peristaltic pump control can be adjusted.
  • The DO value is compensated with temperature to measure the exact value and the value of dead-band for the peristaltic pump control can be adjusted also.
  • The ring shape sparger is made of stainless steel and multiple hole helps uniform foam distribution.
  • All measured data and control parameters are transmitted to the personal computer by RS-232C communication protocol.
  • The graphic user interfaced monitoring program gives all the status of the fermentor system in a full graphic mode.
  • The four channel gas mixer can be attached to the LiFlus GS system.
  • Panel control system shows the measured values of temperature, pH, DO, motor speed and the status of peristaltic pumps at the same time.
  • The motor speed can be governed by the DO value in the DO mode to control the dissolved oxygen level.
  • All the accessaries such as the reagent bottles can be located in the controller body that it needs small space and ease of use.
  • The rotating speed can be limited to protect the damage from the overspeed to the system.

SPECIFICATIONS 

Agitation Drive Top drive motor(mechanical drive)
Range 50~1,200 rpm
Sensor Magentic hall sensor
Impellers 2-Rushton turbine impeller,1-foam breaker
Indication Monolitic LCD display
Temperature Range From 3 above the cooling water temperature to 80 (accuracy 0.1)
Control Digital temperature controller
Sensor Ring sparger
Aeration 2Gas Mode Air, O2
Air Flow,Electronic TMM or TMC
Sparger Ring sparger
Intel Filter 0.2 air filter cartridge
Exhaust System Filter 0.2 air filter cartridge
Condenser SUS316
pH Setpoint/Display Range 2.0~12.0
Control Modes PID maintain with 0.01 pH of setpoint
Electrode Mettler Toledo or Hamilton delectrode
DO Setpoint Range 0~200% 0.1
Display Range 0~200% 0.1
Control Modes PID
Electrode Mettler Toledo or Hamilton delectrode
Pumps Control 4pumps each assignable to a wide variety of function control of acid, base, foam, and feed
Control Cabinet Dimension 420D x 245W x 720H(mm)
Power 220V, 50/60Hz
Recording Output pH, DO, Foam, RS-232C
DO Electric Heater 400 watt
Dimension 250D x 300W x 100H(mm)
Control PID

VESSEL 

Single Vessel
Top Plate (pH, DO, anti-foam, Thermo well, Inoculation, Sampling 4point feeding ports)
Ports Cap, Blade, Foam Breaker, Pyrex Glass condenser, Ring type Sparger,
Removal Baffle Powerful DC Motor, Single Mechanical Seal, Pyrex Glass Vessel silicon Tube,
Vessel Packing, cold Finger Heating Plate (Heater, Water in/out ports)
* Please refer to the below for the specification/price according to volume & type of each item
* Price depends on the type, but some of items have the same price regardless of type.
Catalog Number Total Vol.
(working Vol.)

Inner Dia.
(mm)

Inner Heighta
(mm) 		Electrode Length
(mm) 		Min Vol.
(L) 		Impeller Diameter
(mm)		 D/P
(%)		 H:D
D H P
PF1G2SL02 1.5L (1L) 110 150 120 0.3 60 55 1.3 :1
PF1G2SL03 3L (2.5L) 130 220 120 0.5 60 45 1.7 :1
PF1G2SL05 5L (3L) 145 300 225 1.5 60 42 1.2 :1
PF1G2SL07 7L (5L) 170 310 225 3.2 72 45 1.7 :1
PF1G2SL10 10L (7L) 190 355 320 6 80 42 1.8 :1
   
Double Vessel
Pyrex Glass double Vessel Assembly with Vessel supporter Top Plate (pH,DO,Anti-foam, Thermo well,
Inoculation, Sampling 4poin feeding points). Ports, Blade, Foam Breaker Pyrex Glass Condenser,
Ring type Sparger, Removal Baffle Powerful DC Motor, Seal, Pyrex Glass Vessel Silicon Tube,
Vessel packing, Cold Finger Heating Plate(Heater, water in/out ports)
* Double vessel doesn't need Heating Plate but Water bath for exclusive use
Catalog Number Total Vol.
(working Vol.)

Inner Dia.
(mm)

Inner Heighta
(mm) 		Electrode Length
(mm) 		Min Vol.
(L) 		Impeller Diameter
(mm)		 D/P
(%)		 H:D
D H P
PF1G2DL02 1.5L (1L) 110 150 120 0.3 60 55 1.3 :1
PF1G2DL03 3L (2.5L) 130 220 120 0.5 60 45 1.7 :1
PF1G2DL05 5L (3L) 145 300 225 1.5 60 42 1.2 :1
PF1G2DL07 7L (5L) 170 310 225 3.2 72 45 1.7 :1
   
Bowl Vessel
Pyrex glass single Vessel with BOWL type low plate Top Plate (pH, DO, Anti-foam, Thermo well, Inoculation, Sampling 4 point feeding ports SUS ports Cap, Blade, Foam Breaker Pyrex Glass Condenser, Ring type sparger, Removal Baffle Powerful DC Motor, Single Mechanical Seal, Pyrex Glass Vessel Silicon Tube, Quick coupling, Vessel Packing Heating Plate (Heater, Water in/out ports) * Single/Double vessel has the range up to 10L, impossible for the bigger volume to control the Temp with Cold Finger. Bowel vessel is excellent at freezing vessel because the bottom plate is made of round SUES * BOWL Vessel doesn't need Heating Plate but Water Bath for exclusive use
Catalog Number Total Vol.
(working Vol.)

Inner Dia.
(mm)

Inner Heighta
(mm) 		Electrode Length
(mm) 		Min Vol.
(L) 		Impeller Diameter
(mm)		 D/P
(%)		 H:D
D H P
 
PF1G2DL07 10L (7L) 190 355 320 6 80 42 1.8 :1
PF1G2DL07 14L (10L) 190 500 425 6 80 42 2.6 :1
   

Animal cell Vessel (Depth filter setting)

Mass cultivation of animal cells has intensively been investigated even thought cell culture techniques have been developed for long times.

There have been several difficulties in maintaining large quantities of live cells, especially more than million of cells per m/ in over five liter vessel. Fragility of animal cell, sophisticated culture conditions less economical feasibility of being scaled-up were major bottle necks in idustrializing cell culture technologies to produce a large amount of pharmaceuticals, tPA, interferon, EPO and many other MAb.

 

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